The Mona Lisa is a world-famous portrait painting created by the Italian artist Leonardo da Vinci in the early 16th century. It is renowned for its masterful use of sfumato, a technique that creates soft transitions between colors and tones, contributing to the enigmatic expression of the subject. The painting represents key features of Renaissance art, including a focus on human emotion and the use of perspective, making it a symbol of this transformative period in art history.