Paticca-samuppada, often translated as 'dependent origination,' is a fundamental Buddhist concept that explains the interconnectedness of all phenomena and the cyclical nature of existence. It posits that all things arise in dependence upon conditions and cease when those conditions are no longer present. This concept is essential for understanding the nature of rebirth, as it illustrates how actions (karma) lead to future experiences in an ongoing cycle of birth, death, and rebirth.