Follicular dendritic cells (FDCs) are specialized antigen-presenting cells found in the germinal centers of lymphoid follicles, playing a crucial role in the immune response. They are essential for the activation, proliferation, and differentiation of B cells, facilitating processes like antibody class switching and affinity maturation. By presenting antigens to B cells and providing necessary survival signals, FDCs help generate high-affinity antibodies and maintain memory B cell populations.
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