CR1, or complement receptor 1, is a membrane-bound protein that plays a significant role in the immune system by binding to complement component C3b and aiding in the clearance of immune complexes and pathogens. This receptor is primarily expressed on the surface of immune cells like macrophages and B cells, enhancing their ability to recognize and eliminate opsonized targets through phagocytosis. The functionality of CR1 is vital for maintaining immune homeostasis and preventing excessive inflammation.
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