The La Salle Expedition was a French exploration mission led by Renรฉ-Robert Cavelier, Sieur de La Salle, in the late 17th century that aimed to establish a French presence in the Mississippi River Valley and surrounding regions, including Texas. The expedition's failures and subsequent establishment of a French settlement prompted Spain to reassess and reinforce its colonial policies in the area, leading to increased military presence and the establishment of missions to counter French influence.