A nuclear chain reaction is a process where a single nuclear reaction causes a series of further reactions, leading to a rapid release of energy. This occurs when a fissile material, such as uranium-235 or plutonium-239, undergoes fission, releasing neutrons that can then induce fission in nearby nuclei. The result is a self-sustaining series of reactions that can produce massive amounts of energy, making it critical for both nuclear reactors and atomic bombs.