The Yamasee War was a conflict that took place from 1715 to 1717 between the English settlers in South Carolina and various Native American tribes, primarily the Yamasee tribe. This war arose from growing tensions due to land encroachments, trade disputes, and the exploitation of Native Americans by European settlers. The conflict marked a significant turning point in the early interactions between European settlers and Native Americans, leading to a reevaluation of colonial policies and relationships with Indigenous peoples.