'Night Comes to the Cumberlands' is a significant work by Harry Caudill published in 1962 that critiques the socio-economic conditions of the Appalachian region, particularly Kentucky. The book sheds light on the struggles faced by the local population due to exploitation by outside interests, such as coal companies, and highlights the cultural identity of Appalachians amid these challenges. Through vivid narratives and personal accounts, it also addresses issues of poverty, environmental degradation, and the fight for dignity and justice among the Appalachian people.