Pressure drop (δp) refers to the reduction in pressure along a flow path due to frictional forces and other resistive effects, which can occur in fluids moving through a channel or over a surface. This concept is critical for understanding how energy is dissipated in heat and mass transfer processes, particularly at the microscale where flows can be dominated by surface interactions. The pressure drop is an essential factor in designing systems for efficient heat exchange, as it influences flow rates and temperature distributions.