Histone acetyltransferases (HATs) are enzymes that add acetyl groups to the amino-terminal tails of histone proteins, a process that plays a crucial role in the regulation of gene expression and chromatin structure. By acetylating histones, HATs promote a more relaxed chromatin configuration, facilitating access to DNA for transcription and thereby influencing cellular differentiation. The activity of HATs is vital for the activation of genes required during various developmental processes.
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