Path-independent line integrals are integrals where the value of the integral depends only on the endpoints of the path, not on the specific route taken between them. This property implies that if a vector field is conservative, then the line integral calculated along any path connecting two points will yield the same result. In relation to Stokes' theorem, these integrals highlight the relationship between vector fields and their potential functions, showing how certain vector fields can lead to consistent results regardless of path.