Rotenone is a natural compound derived from the roots of certain plants, particularly those in the Fabaceae family, known for its ability to inhibit mitochondrial electron transport. This inhibition is primarily targeted at Complex I of the electron transport chain, disrupting the flow of electrons and ultimately affecting ATP production. The effects of rotenone on cellular respiration highlight its significance as both a pesticide and a tool in biochemical research to study mitochondrial function.
congrats on reading the definition of rotenone. now let's actually learn it.