โš—๏ธbiological chemistry ii review

Muscle growth

Written by the Fiveable Content Team โ€ข Last updated September 2025
Written by the Fiveable Content Team โ€ข Last updated September 2025

Definition

Muscle growth, also known as hypertrophy, is the process by which skeletal muscle fibers increase in size and cross-sectional area in response to resistance training and various physiological stimuli. This process is influenced by several factors, including hormonal regulation, nutrition, and mechanical tension on the muscles, all of which are important for enhancing strength and physical performance.

5 Must Know Facts For Your Next Test

  1. Muscle growth primarily occurs through two types: myofibrillar hypertrophy, which increases muscle strength, and sarcoplasmic hypertrophy, which enhances endurance capacity.
  2. Testosterone plays a crucial role in muscle growth by stimulating protein synthesis and promoting satellite cell activation, essential for muscle repair and growth.
  3. An adequate intake of protein is necessary for muscle repair and growth, with recommendations typically suggesting 1.6 to 2.2 grams of protein per kilogram of body weight for those looking to build muscle.
  4. Resistance training leads to micro-tears in muscle fibers; during recovery, the body repairs these fibers by fusing them together, resulting in thicker and stronger muscles.
  5. A well-structured training program that includes progressive overloadโ€”gradually increasing weights or resistanceโ€”is vital for continuously stimulating muscle growth.

Review Questions

  • How do anabolic steroids influence muscle growth, and what are the potential risks associated with their use?
    • Anabolic steroids enhance muscle growth by mimicking testosterone's effects, promoting increased protein synthesis and reducing the breakdown of muscle tissue. This results in accelerated hypertrophy and improved performance in strength-based activities. However, the potential risks of using anabolic steroids include hormonal imbalances, liver damage, cardiovascular issues, psychological effects like aggression, and dependence. Therefore, while they can significantly enhance muscle growth, their use can lead to serious health consequences.
  • Discuss the role of nutrition in supporting muscle growth during a resistance training program.
    • Nutrition plays a vital role in supporting muscle growth during resistance training by providing the necessary nutrients for recovery and adaptation. A balanced diet rich in protein is essential for repairing muscle tissue post-exercise; carbohydrates are crucial for replenishing glycogen stores used during workouts. Additionally, healthy fats support hormone production that regulates muscle growth. Timing of nutrient intake around workouts can also optimize recovery and anabolic responses, further promoting hypertrophy.
  • Evaluate how mechanical tension from resistance training contributes to the biochemical processes involved in muscle growth.
    • Mechanical tension from resistance training is a key factor in initiating muscle growth by signaling various biochemical pathways that lead to hypertrophy. When muscles are subjected to tension, they experience microtrauma, which activates satellite cells and triggers the release of growth factors like IGF-1 and mTOR. These factors stimulate protein synthesis and inhibit degradation pathways, promoting an increase in muscle fiber size. By consistently applying progressive overload through resistance training, individuals can maximize these biochemical responses and enhance their overall muscle development.

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