Substance abuse refers to the excessive and harmful use of drugs or alcohol, leading to negative consequences on physical and mental health, as well as social functioning.
Withdrawal refers to the symptoms experienced when someone stops using a drug or alcohol after prolonged use. These symptoms can range from mild discomfort to severe physical and psychological distress.
Tolerance is the body's adaptation to a specific substance, requiring higher doses over time to achieve the desired effect. It can contribute to an increased risk of addiction and overdose.