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Selective Serotonin Reuptake Inhibitors (SSRIs)

Definition

SSRIs are a type of antidepressant medication that increase the level of serotonin, a neurotransmitter associated with feelings of well-being and happiness, in the brain by preventing its reabsorption into the neurons.

Analogy

Think of SSRIs as a dam on a river. The river represents serotonin flowing through your brain. Normally, some water (serotonin) gets absorbed back into the ground (neurons). But when you build a dam (take an SSRI), more water stays in the river, increasing its overall level.

Related terms

Serotonin: A neurotransmitter that regulates mood, appetite, and sleep.

Neurotransmitter: Chemicals that transmit signals from one neuron to another.

Antidepressants: Medications designed to reduce or prevent symptoms of depression.

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AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.