Resistant to Medication

Definition

When an individual diagnosed with a mental health condition, such as major depressive disorder, does not show significant improvement in symptoms despite trying multiple medications at appropriate doses and durations.

Related terms

Treatment-Resistant Depression (TRD): TRD refers specifically to major depressive disorder that doesn't respond adequately to several trials of antidepressant medications.

Augmentation Therapy: Augmentation therapy involves adding another medication or treatment alongside existing antidepressant medication(s) to enhance their effectiveness for individuals who are resistant to traditional treatments.

Electroconvulsive Therapy (ECT):

ECT is a procedure that involves passing electric currents through the brain under anesthesia. It can be effective for individuals who haven't responded well to medications or other forms of treatment.