Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
PYY (Peptide YY) is a hormone that helps regulate appetite. It's released by cells in the intestines and colon after eating, signaling to your brain that you're full.
This is known as the 'hunger hormone' because it stimulates appetite, increases food intake and promotes fat storage.
Cholecystokinin (CCK): This is another hormone that aids digestion and reduces appetite. It acts as an antagonist to ghrelin.
Glucagon-like peptide-1 (GLP-1): A hormone involved in regulating blood sugar levels and slowing down gastric emptying which can lead to feelings of satiety.