Tolerance: Tolerance refers to the reduced effect of a drug after repeated use. Over time, larger doses are needed to achieve the same desired effect.
Withdrawal: Withdrawal is a set of physiological and psychological symptoms that occur when someone stops using a psychoactive substance after prolonged use.
Addiction: Addiction is characterized by compulsive drug-seeking behavior despite negative consequences. It involves both physical dependence (tolerance and withdrawal) and psychological dependence (craving and loss of control).