Written by the Fiveable Content Team โข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโขWritten by the Fiveable Content Team โข Last updated September 2025
Definition
Major depressive disorder (MDD) is a mental health disorder characterized by persistently depressed mood or loss of interest in activities causing significant impairment in daily life.
Related terms
Dysthymia: Persistent mild depression lasting for at least two years.