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Manipulate refers to the act of purposely altering or controlling something, often for experimental purposes. In the context of neuroscience, it involves intentionally changing or influencing a specific aspect of neuronal activity.
The deliberate interference or alteration in a system or process.
Modulate: The act of adjusting or regulating something to achieve a desired effect.
To encourage or provoke a response in something, such as stimulating neuronal activity through external means.