Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
First-line treatment refers to the initial course of therapy or medication prescribed by clinicians. It is typically the most effective and recommended option for treating a specific condition.
Related terms
Second-line treatment: If the first-line treatment fails to produce desired results or causes intolerable side effects, clinicians may recommend alternative therapies as second-line treatments.
Evidence-based practice: The approach where clinicians make decisions based on scientific evidence from research studies and clinical trials when choosing first-line treatments.
Treatment-resistant schizophrenia: A term used when individuals with schizophrenia do not respond well to first-line treatments despite adequate dosage and duration.