Written by the Fiveable Content Team โข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโขWritten by the Fiveable Content Team โข Last updated September 2025
Definition
Leptin is a hormone produced by fat cells that signals the hypothalamus in the brain about our body fat level. When working properly, leptin helps maintain our body weight within a healthy range.
Related terms
Adiponectin: A protein hormone involved in regulating glucose levels and fatty acid breakdown.
Resistin: A hormone associated with obesity; it's believed to play a role in insulin resistance.
Obestatin: A peptide hormone thought to suppress hunger and decrease food intake.