Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
Functionality refers to the degree to which something operates effectively or fulfills its intended purpose. In the context of the HPA axis, it refers to how well this neuroendocrine system functions under normal or stressed conditions.
Homeostasis is the body's ability to maintain internal stability by adjusting its physiological processes in response to changes in external conditions. It involves keeping variables within narrow ranges for optimal function.
Negative Feedback Loop: Negative feedback loop is a regulatory mechanism where a change from an ideal set point triggers a response that counteracts or reverses the change. In the HPA axis, cortisol release triggers a negative feedback loop to inhibit further cortisol production.
Neuroplasticity refers to the brain's ability to reorganize its structure and function in response to experiences and environmental changes. It allows for adaptation and learning throughout life.