Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
The depolarization process refers to the change in a cell’s membrane potential, making it more positive and initiating an action potential.
Related terms
Hyperpolarization: This is when changes in membrane potential make the inside of a cell even more negative than usual. It's like adding extra locks on your door before going out.
Repolarization: After depolarization occurs and an action potential has been initiated, repolarization restores the original resting state of negative internal charge relative to outside. It’s akin to closing and locking your door after your friend leaves.
This is the time following an action potential during which a new action potential cannot be initiated. It's like needing a few moments to settle back in before you're ready to answer the door again.