Written by the Fiveable Content Team โข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโขWritten by the Fiveable Content Team โข Last updated September 2025
Definition
The principle stating that once an action potential is initiated, it will always fire at full strength. There is no partial or graded response; either it occurs completely or not at all.
Related terms
Subthreshold Stimulus: A stimulus that is not strong enough to generate an action potential in a neuron.
Overshoot: The phase during an action potential where the voltage inside the neuron becomes more positive than resting membrane potential.