๐Ÿงชap chemistry review

Henderson-Hasselbalch Equation

Written by the Fiveable Content Team โ€ข Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 examโ€ขWritten by the Fiveable Content Team โ€ข Last updated September 2025

Definition

The Henderson-Hasselbalch equation is a mathematical formula used to calculate the pH of a solution given the pKa (acid dissociation constant) and the ratio of the concentrations of the acid and its conjugate base.

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