💀anatomy and physiology i review

Zone of maturation and hypertrophy

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The zone of maturation and hypertrophy is a region in the growth plate of long bones where chondrocytes (cartilage cells) enlarge and mature. This area is crucial for bone lengthening as it prepares cartilage to be replaced by bone tissue.