💀anatomy and physiology i review

Stratum granulosum

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The stratum granulosum is a thin layer of the epidermis located between the stratum spinosum and the stratum lucidum, characterized by cells that appear granular due to the presence of keratohyalin granules. These granules play a key role in the process of keratinization, which provides a barrier against environmental damage.

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