Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
A naïve lymphocyte is an immature lymphocyte that has not yet encountered its specific antigen. These cells circulate in the blood and lymphatic system, ready to initiate an immune response upon encountering their corresponding antigen.
Related terms
Antigen: A substance that when introduced into the body stimulates an immune response, specifically the production of antibodies.
Immune response: The reaction of the immune system against foreign substances (antigens) invading the body.
Lymphatic system: A network of tissues and organs that help rid the body of toxins, waste, and other unwanted materials, playing a vital role in hosting the immune response