💀anatomy and physiology i review

Megakaryocyte

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

A megakaryocyte is a large bone marrow cell responsible for the production of blood thrombocytes (platelets), which are crucial for blood clotting. These cells undergo a process called endomitosis, where they replicate their DNA without cell division, leading to an increase in cell size and nuclear content.