Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Histones are proteins found in the nuclei of eukaryotic cells that package and order the DNA into structural units called nucleosomes. They play a crucial role in gene regulation and DNA replication, repair, and recombination.
Related terms
Nucleosome: The fundamental unit of chromatin, consisting of a segment of DNA wound around eight histone proteins.