Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Extracellular fluid is the body fluid located outside the cells, serving as a medium for the exchange of substances between cells and their environment. It includes fluids found in blood vessels and interstitial spaces that surround cells.
Related terms
Interstitial Fluid: The part of extracellular fluid that fills the spaces between most cells of the body, providing a constant environment for cells to function.
The liquid component of blood that is part of extracellular fluid where blood cells are suspended, involved in transporting nutrients, waste products, and other substances.
The process by which an organism maintains a stable internal environment despite changes in external conditions; ECF plays a critical role in this process