Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
The eponychium is a small band of epidermis located at the base of the fingernails and toenails. It functions as a protective barrier, preventing pathogens from entering the nail matrix.
Related terms
Cuticle: The thin layer of dead skin that rides on the surface of the nail, often mistaken as part of the eponychium.
Nail matrix: The tissue under the nail that produces cells that become the nail plate.