Itemized deductions offer taxpayers a way to reduce taxable income by claiming specific expenses. These deductions, reported on Schedule A, include medical costs, state and local taxes, mortgage interest, and charitable donations, each subject to various limitations and requirements. The Tax Cuts and Jobs Act of 2017 significantly impacted itemized deductions, increasing standard deduction amounts and modifying rules for specific deductions. Understanding these changes helps taxpayers decide between itemizing and taking the standard deduction to minimize their tax liability.