Avian malaria in Hawaiian honeycreepers refers to a parasitic disease caused by the protozoan Plasmodium that significantly impacts these endemic bird species in Hawaii. The introduction of non-native mosquito species has facilitated the spread of avian malaria, posing a severe threat to the already vulnerable Hawaiian honeycreepers, which have evolved in isolation and lack immunity to this disease. The interaction between invasive mosquitoes and native birds highlights the ecological consequences of introduced species and their role in disease transmission.