Spanish colonial rule in New Spain transformed Mexico's political, economic, and social landscape. The conquest of the Aztec Empire by Hernán Cortés in 1521 marked the beginning of Spanish dominance, establishing a complex system of governance and exploitation. The colonial period saw the imposition of Spanish institutions, including the Catholic Church and a rigid social hierarchy based on race. Indigenous populations faced exploitation and disease, while cultural fusion led to the emergence of mestizo identity and unique colonial art forms.