Stage of resistance

Definition

In the context of the endocrine system and its interaction with the adrenal glands, the stage of resistance is a phase within the general adaptation syndrome where the body adapts to a continued stressor through increased hormonal signals, primarily cortisol. This stage follows the initial fight-or-flight response and aims to restore homeostasis while resisting the effects of a persistent stressor.

Related terms

General Adaptation Syndrome (GAS): A three-phase response model (alarm, resistance, exhaustion) that describes the body's short-term and long-term reactions to stress.

Cortisol: A steroid hormone produced by the adrenal glands that plays a key role in glucose metabolism, blood pressure regulation, insulin release for blood sugar maintenance, immune function, and inflammatory response.

Adrenal Glands:

Endocrine glands located above the kidneys that produce various hormones including adrenaline, noradrenaline, and cortisol which are crucial for stress response, metabolism, and immune system regulation