Juxtaglomerular apparatus (JGA)

Definition

The juxtaglomerular apparatus is a specialized structure formed by the distal convoluted tubule and the glomerular afferent arteriole in the kidney. It plays a crucial role in regulating blood pressure and the filtration rate of the kidneys.

Related terms

Glomerulus: A network of capillaries located at the beginning of a nephron in the kidney that filters blood to form urine.

Distal Convoluted Tubule:

A portion of kidney nephron between the loop of Henle and the collecting duct system where selective reabsorption and secretion occur, further refining urine.

Renin:

An enzyme secreted by juxtaglomerular cells when reduced blood pressure is detected, initiating a series of reactions that raise blood pressure