Erythropoietin (EPO)

Definition

Erythropoietin (EPO) is a hormone produced mainly by the kidneys that plays a key role in the production of red blood cells. It signals the bone marrow to increase the production of red blood cells in response to low oxygen levels in tissues.

Related terms

Hematopoiesis:

The process by which all the formed elements of blood (red cells, white cells, and platelets) are produced in the bone marrow.

Hypoxia:

A condition in which there is insufficient oxygen reaching tissues, often triggering an increase in erythropoietin production.

Bone marrow: A spongy tissue inside bones where hematopoiesis occurs, including the production of red blood cells under the influence of erythropoietin