Coenzyme: This is like rechargeable batteries. Itโs a type of cofactor that are organic molecules and can be reused in multiple reactions.
Prosthetic Group: This would be like built-in, non-removable batteries. Theyโre permanently bound to their enzymes.
Apoenzyme/Holoenzyme: These are like your remote control car without/with batteries. Apoenzyme is inactive enzyme without its cofactor while holoenzyme is active with its cofactor.