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Meningitis

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Anatomy and Physiology I

Definition

Meningitis is an inflammation of the protective membranes, called the meninges, surrounding the brain and spinal cord. This condition can be caused by infections from viruses, bacteria, or fungi, and can lead to serious complications if not treated promptly. During a neurological exam, signs of meningitis may be assessed through various tests that evaluate neurological function and the presence of specific symptoms like neck stiffness and altered mental status.

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5 Must Know Facts For Your Next Test

  1. Meningitis can present with symptoms such as severe headache, fever, and a stiff neck, which are critical indicators during a neurological exam.
  2. Bacterial meningitis is typically more severe than viral meningitis and requires urgent medical intervention, often involving antibiotics.
  3. Certain populations, such as college students living in dormitories, are at higher risk for bacterial meningitis due to close living quarters.
  4. Vaccination can significantly reduce the incidence of some types of bacterial meningitis, particularly those caused by Neisseria meningitidis and Streptococcus pneumoniae.
  5. Diagnosis of meningitis often involves a combination of clinical assessment and lumbar puncture to analyze CSF for the presence of pathogens or inflammatory markers.

Review Questions

  • What clinical signs would you expect to observe in a patient suspected of having meningitis during a neurological exam?
    • In a patient suspected of having meningitis, key clinical signs during a neurological exam would include a severe headache, photophobia (sensitivity to light), neck stiffness, and possible altered mental status. Additionally, the presence of a positive Brudzinski's sign (involuntary lifting of the legs when the neck is flexed) or Kernig's sign (inability to straighten the leg when the hip is flexed) can further indicate meningeal irritation.
  • How does a lumbar puncture aid in the diagnosis of meningitis, and what findings would you expect?
    • A lumbar puncture is essential for diagnosing meningitis as it allows for direct analysis of cerebrospinal fluid (CSF). In cases of bacterial meningitis, the CSF may appear cloudy or turbid with elevated white blood cell counts, predominantly neutrophils, and increased protein levels, while glucose levels may be decreased. In contrast, viral meningitis usually shows lymphocytic pleocytosis with normal glucose levels. These findings help differentiate between the types of meningitis.
  • Evaluate the implications of untreated bacterial meningitis on neurological health and how timely intervention alters outcomes.
    • Untreated bacterial meningitis can lead to severe complications such as permanent neurological damage, hearing loss, or even death due to the rapid progression of inflammation and infection. The inflammatory response can cause swelling within the cranial cavity and increased intracranial pressure, leading to brain injury. Timely intervention with appropriate antibiotics can significantly improve outcomes by reducing morbidity and mortality associated with the disease. Early recognition and treatment are crucial in preventing long-term consequences on neurological health.
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