Opsonization is the process by which pathogens are marked for ingestion and destruction by phagocytes. This marking involves the coating of antigens with opsonins, such as antibodies or complement proteins.
5 Must Know Facts For Your Next Test
Opsonization enhances the efficiency of phagocytosis by marking pathogens for destruction.
Major opsonins include antibodies (IgG) and complement proteins (C3b).
Phagocytes have receptors that specifically bind to opsonins, facilitating pathogen uptake.
Opsonization plays a crucial role in both innate and adaptive immunity.
Deficiencies in opsonization can lead to increased susceptibility to infections.