The Treaty of New Echota was an agreement signed in 1835 between the U.S. government and a small faction of the Cherokee Nation, which resulted in the forced removal of the Cherokee people from their ancestral lands in the southeastern United States to designated territory west of the Mississippi River. This treaty was a pivotal moment in the context of land policies and westward expansion, leading to what is known as the Trail of Tears, where thousands of Cherokee suffered during their relocation.