Flow of trade refers to the movement of goods, services, and commodities between different regions or countries, significantly influencing economic interactions and cultural exchanges. This concept is critical to understanding the Columbian Exchange, as it highlights how the introduction of new products and resources between the Old and New Worlds reshaped economies and societies. The flow of trade during this period established new trade routes and networks that facilitated not just economic growth but also the spread of ideas, technologies, and even diseases across continents.