Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
A synapse is a specialized junction between two neurons or between a neuron and its target cell where communication occurs. It allows for the transmission of electrical or chemical signals from one cell to another.
Related terms
Presynaptic Neuron: A presynaptic neuron is the sending neuron in a synapse that releases neurotransmitters into the synaptic cleft.
Postsynaptic Neuron: A postsynaptic neuron is the receiving neuron in a synapse that contains receptors for binding with neurotransmitters released by presynaptic neurons.
Synaptic Cleft: The synaptic cleft is a small gap between the presynaptic and postsynaptic neurons where neurotransmitters are released and travel across to bind with receptors.