Gas gangrene

Definition

Gas gangrene is a severe bacterial infection that produces gas within tissues. It is typically caused by Clostridium species, especially Clostridium perfringens.

5 Must Know Facts For Your Next Test

1. Clostridium perfringens is the most common causative agent of gas gangrene.
2. Gas gangrene can rapidly progress and requires immediate medical attention, often involving surgical intervention.
3. The bacteria produce toxins and enzymes that facilitate tissue destruction and gas production.
4. Anaerobic conditions are necessary for the growth of Clostridium species causing gas gangrene.
5. Symptoms include severe pain, swelling, pale to dark red skin discoloration, and crepitus due to gas formation under the skin.

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Related terms

Clostridium perfringens:

A Gram-positive, anaerobic bacterium known for causing food poisoning and gas gangrene.

Crepitus: A crackling sensation felt under the skin due to gas bubbles produced by certain bacterial infections.

Anaerobic bacteria: Bacteria that do not require oxygen for growth and may even die in its presence.