Intro to Brain and Behavior
The dopamine hypothesis suggests that an overactivity of dopamine transmission in certain brain regions is a key factor in the development of schizophrenia and other psychotic disorders. This theory connects the symptoms of these disorders, such as hallucinations and delusions, to the dysregulation of dopamine, particularly in areas like the mesolimbic pathway. It also highlights how antipsychotic medications, which primarily target dopamine receptors, can alleviate these symptoms, further supporting this hypothesis.
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