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Transfer RNA (tRNA)

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Transfer RNA (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. It functions by carrying specific amino acids to the ribosome during protein synthesis.

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5 Must Know Facts For Your Next Test

  1. 1. tRNA has a cloverleaf structure with an anticodon loop that pairs with the mRNA codon.
  2. 2. Each tRNA molecule is specific to one amino acid, which it carries to the ribosome.
  3. 3. The 3' end of the tRNA is where the amino acid attaches.
  4. 4. Aminoacyl-tRNA synthetases are enzymes that charge tRNAs with their respective amino acids.
  5. 5. There are different tRNAs for each codon in the genetic code except for stop codons.

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