Depolarization is the process by which a neuron's membrane potential becomes less negative, moving closer to zero. This change is crucial for the initiation and transmission of electrical signals in neurons.
5 Must Know Facts For Your Next Test
Depolarization occurs when sodium ions (Na+) flow into the neuron through voltage-gated sodium channels.
It is a key phase in the generation of an action potential.
Depolarization must reach a certain threshold potential to trigger an action potential.
The rapid influx of Na+ during depolarization causes the inside of the neuron to become positively charged relative to the outside.
Following depolarization, repolarization occurs to restore the neuron's resting membrane potential.
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Related terms
Action Potential: A rapid rise and subsequent fall in membrane potential that propagates along the axon of a neuron.