R-squared, also known as the coefficient of determination, measures the proportion of the variance in the dependent variable that can be explained by the independent variable(s) in a regression model. It provides insight into how well the regression model fits the data, indicating the strength and reliability of the relationship between the variables. A higher R-squared value suggests a better fit and more predictive power, while a lower value indicates that the model does not explain much of the variability in the dependent variable.